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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FIGN All Species: 28.79
Human Site: S739 Identified Species: 42.22
UniProt: Q5HY92 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5HY92 NP_060556.2 759 82146 S739 A F C K I Q P S I S Q K E L D
Chimpanzee Pan troglodytes XP_001153855 674 74011 V655 F R T V R P S V S P K D L E L
Rhesus Macaque Macaca mulatta XP_001097992 759 82110 S739 A F C K I Q P S I S Q K E L D
Dog Lupus familis XP_545496 695 74019 I676 F C K I Q P S I S Q K E L D M
Cat Felis silvestris
Mouse Mus musculus Q9ERZ6 759 82080 S739 A F C K I Q P S I S Q K E L D
Rat Rattus norvegicus Q6GX84 677 74178 V658 F R T V R P S V S P K D L E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506217 731 78137 S711 A L G T V R P S V S P R D L E
Chicken Gallus gallus Q5ZK92 613 66247 S594 K K I K R S L S P Q T L E A Y
Frog Xenopus laevis Q6DDU8 655 72133 S635 A F L V V R P S V S Q K D L E
Zebra Danio Brachydanio rerio Q503S1 736 79183 S716 V F C K I Q P S I S Q K E L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQN8 523 58530 V504 L R V I S K S V S S E D C K Q
Honey Bee Apis mellifera XP_625184 585 66969 T566 S V S E S S L T T Y V E W D A
Nematode Worm Caenorhab. elegans O16299 594 66169 D575 T V D D S Q L D A Y A A W D K
Sea Urchin Strong. purpuratus XP_783737 603 65189 Q584 N V R P S V A Q S D L D S Y L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SEX2 523 57218 S504 A I R K V Q P S V S S S D I E
Baker's Yeast Sacchar. cerevisiae P39955 897 100313 S876 S L V Y I K P S V S Q D G L V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.6 99.4 72.9 N.A. 97.8 35.5 N.A. 31.6 24.8 35.7 71.2 N.A. 25.2 26.6 26.4 30.8
Protein Similarity: 100 54.9 99.4 79.1 N.A. 99.3 54.9 N.A. 47 42.2 53.4 83.7 N.A. 40.8 46.6 43.3 46.9
P-Site Identity: 100 0 100 0 N.A. 100 0 N.A. 33.3 20 53.3 93.3 N.A. 6.6 0 6.6 0
P-Site Similarity: 100 6.6 100 13.3 N.A. 100 6.6 N.A. 73.3 20 86.6 93.3 N.A. 20 26.6 6.6 0
Percent
Protein Identity: N.A. N.A. N.A. 23.9 25 N.A.
Protein Similarity: N.A. N.A. N.A. 39.2 40.5 N.A.
P-Site Identity: N.A. N.A. N.A. 40 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 38 0 0 0 0 0 7 0 7 0 7 7 0 7 7 % A
% Cys: 0 7 25 0 0 0 0 0 0 0 0 0 7 0 0 % C
% Asp: 0 0 7 7 0 0 0 7 0 7 0 32 19 19 25 % D
% Glu: 0 0 0 7 0 0 0 0 0 0 7 13 32 13 19 % E
% Phe: 19 32 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 7 0 0 0 0 0 0 0 0 0 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 7 13 32 0 0 7 25 0 0 0 0 7 0 % I
% Lys: 7 7 7 38 0 13 0 0 0 0 19 32 0 7 7 % K
% Leu: 7 13 7 0 0 0 19 0 0 0 7 7 19 44 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % M
% Asn: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 7 0 19 50 0 7 13 7 0 0 0 0 % P
% Gln: 0 0 0 0 7 38 0 7 0 13 38 0 0 0 7 % Q
% Arg: 0 19 13 0 19 13 0 0 0 0 0 7 0 0 0 % R
% Ser: 13 0 7 0 25 13 25 57 32 57 7 7 7 0 0 % S
% Thr: 7 0 13 7 0 0 0 7 7 0 7 0 0 0 0 % T
% Val: 7 19 13 19 19 7 0 19 25 0 7 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 13 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _